Friday, March 28, 2008

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Is TNF Inhibitor Use Associated with a Reduced Risk of Myocardial Infarction in Rheumatoid Arthritis?

Fri, 28 Sep 2007 10:43:37 -0500
RA is associated with an increase in cardiovascular (CV) events, such as myocardial infarction (MI) and sudden cardiac death. Inflammatory cytokines, such as TNF-α, are implicated in atherothrombosis and the RA disease state, potentially explaining the increased risk of CV events in RA. The use of TNF inhibitors was associated with a reduced risk of cardiovascular events in RA patients in one study, although it is not clear whether these effects are due to unique features of TNF inhibitors or are a consequence of non-specific suppression of inflammation. Here, Dixon et al (Arthritis Rheum 2007; 56(9): 2905) explore these issues in analyses of participants enrolled in the British Society for Rheumatology Biologics Register (BSRBR).

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Arthritis is one of the most fatal diseases in the world, and this is on account of the number of casualties it has claimed in the United States and other parts of the world. After spending millions of dollars to combat this deadly disease, there is still no end in sight in terms of a permanent solution. Even with this state of affairs, victims of the disease should not lose hope because it is certainly not the end of the world. Obtain a effective prolonged stroll at least thrice a week or enlist in a step-aerobics or low-impact training exercise habit for optimum results.



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Nevertheless, additional therapeutic measures should be considered if clinical course is complicated by arthritis.



Radiographs are often used to follow progression or assess severity in a more quantitative manner.



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A physical therapist will explicate the value of certain activities and propose exercises suited to your youngster's detailed infirmity. Family members may play worthy roles in helping a teen cope with juvenile rheumatoid arthritis.
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